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Reply Marie Curie Hall of Science
Chemistry and Biology

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PostPosted: Tue Oct 01, 2019 10:05 pm


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gaia_zurg


Be less curious about people and more curious about ideas.


This unit provides you with an introduction to the classification of bioactive compounds according to the various physiological systems they influence, such as the cardiovascular system, nervous system and respiratory system. The principles of drug action will be discussed, including the concepts of drug specificity, potency and efficacy. These principles will facilitate a basic understanding of toxicology, the development drug tolerance, addiction and withdrawal. The unit will be taught in the context human and veterinary medicine, as well as the use of drugs in sport, as poisons, or as food or environmental contaminants. The unit complements 'Drug Discovery and Design' offered in the same semester. Fundamental concepts and practical skills relevant to plant medicinal biology, chemistry, biochemistry, and pharmacology. It introduces the general classes of medicinal plant compounds, their biosynthesis and function in planta, their purification and analysis, and clinical applications. The unit introduces the pharmacology of specific plant-derived compounds, thereby building upon the knowledge of drug action developed in BVB212. It provides a deeper understanding of the broader technical, social, cultural, and legal challenges in the transition from discovery to application via focused evaluation of existing/emerging global health challenges. The ability to critically evaluate scientific literature, synthesise information, and write effectively is further developed in this unit. This unit develops a broad range of knowledge and practical skills of direct relevance to the pharmaceutical sector, as well as natural product chemistry, plant science, botany, and allied health.

This unit provides a brief introduction to the history and evolution of drug discovery, including the role of the pharmaceutical industry, to current-day methods including rational computer-aided drug design, drug targets and screening libraries. Case studies may include synthetic hormones, narcotics, chemotherapeutic agents and performance-enhancing compounds. You will be introduced to the concepts of chemical structure and structure-activity relationships. The unit complements 'Drug Action' offered in the same semester. This unit provides an introduction to the basics of bio-analytical methods used for the detection and identification of bio-active substances in different matrices. The methods are demonstrated to bio-active compounds that are frequently encountered in pharmaceutical, forensic, molecular diagnostics and environmental industries. The unit will introduce modern instrumental analytical platforms such as spectroscopy, chromatography, electrophoresis, nanosensors and immunoassay.



 
PostPosted: Tue Oct 08, 2019 9:16 pm


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The teacher for this class (major) is
Aurellia Bernard


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The teacher for this class (minor) is
Hassan Bernard
 

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Marie Curie Hall of Science

 
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